Optimization and Characterization of Cannabis Extracts Obtained By Supercritical Fluid Extraction

PDF Review: 20170719-infinity-supercritical-sco2-review

Source Review: Authors: Omar, J., Olivares, M., Alzaga, M., and Etxebarria, N. (2013).

Title: Optimization and characterization of marihuana extracts obtained by supercritical fluid extraction and focused ultrasound extraction and retention time locking GC-MS.

Journal of Separation Science, 36(8), 1397-1404.

Several monoterpenes and sesquiterpenes are responsible for the unique and strong smell of the cannabis plant.

Terpenes are compounds in a group of naturally occurring volatile unsaturated hydrocarbons built off of isoprene which has the molecular C5H8, with monoterpenes having the structure C10H16 and sesquiterpenes having the structure C15H24.

While sesquiterpenes are in lower amounts in the buds of the cannabis plant, through drying the plant gives off a greater loss of monoterpenes, which would mean most of the smell of the plant while drying is from the monoterpenes.

Monoterpenes are mostly unstable and thus can be easily altered or destroyed in many normal extraction techniques, which has led to much focus on using supercritical fluid extraction (SFE) with CO2 to extract them.

Terpenes are miscible in CO2 at low temperatures and pressures while many non- volatile compounds (like cannabinoids) are not, which mean they can be extracted separately.

Due to these miscibility differences, two different optimal extraction parameters were found when trying to optimize the extraction yield for terpenes or for cannabinoids.

The extraction parameters investigated included pressures between 100 bar (1450psi) and 250 bar (3626 psi), temperatures between 35 (95 F) and 55 C (131 F), flow of solvent between 1-2 ml/min (extracting 100mg of plant matter), and addition of ethanol as a cosolvent between 0 and 40 percent by weight.

In reference to terpenes, temperature and ethanol percentage were significant, with low temperature and no ethanol being the best conditions.

In reference to cannabinoids, only ethanol percentage was found to be significant, with mild ethanol percentages being found to be most efficient.

Due to the insignificance of the other factors,

100 bar (3626 psi), 35 degrees Celsius (95 F), and a solvent feed of 1 ml/min are both optimal for terpenes and for cannabinoids, while 0 percent of ethanol is best for terpenes and 20 percent is best for cannabinoids.

It was also found that different cannabis strains had different concentrations of cannabinoids and terpenes.

For example, Critical and Amnesia are richer in cannabinoids than Somango, AK-47 and 1024.

Also in respect to terpenes, Critical species had the highest concentrations of alpha- pinene and beta-pinene and Amnesia has the highest concentrations of limonene.

Out of all the five species, five monoterpenes, twelve sesquiterpenes, and eight cannabinoids were able to be positively identified and quantified.

The separate extraction of terpenes and cannabinoids is important because terpenes contain their own therapeutic benefits and thus can be used without the psychotropic effects of the cannabinoids.

 

The optimal conditions mean one could extract all the terpenes first and then flush the system with ethanol to extract all the cannabinoids without changing the other parameters. To back this up, in a subsequent extraction as detailed above, all of the monoterpenes were found in the no ethanol extraction and only contain trace amounts of three of the eight cannabinoids.

 

The study also investigated the optimal extraction parameters of using focused ultrasound extraction with isopropanol and cyclohexane and found the best conditions for overall extraction were 3 s(-1) cycles, 80 percent of amplitude on the sonicator, 5 minutes of sonication time with a 1:1 mixture of isopropanol and cyclohexane.

While this extraction yielded slightly more overall extraction than the SFE, it didn’t allow for the selectivity of the terpenes and the cannabinoids.

Thus it is recommended that SFE CO2 is used for cannabis extraction’s due to the minimal difference in yields, the selectivity it offers, the food-safe nature of it, and the low-flammability of the solvent.

Technology Review of Cell Lysis Methods

PDF Download: 20170718-infinity-supercritical-cell-lysis-methods

 

Plant Cell Pressure |Strength of Plant Cell Walls | Ways to Break Cell Walls

 

How to Break Down Cell Walls:

Mechanical:

-Grinding: Mortar and pestle, which is often done with plants frozen in liquid nitrogen.

-Beadbeating: Cracking open cells using ceramic or glass beads, typically done in suspension and in a vortex.
-Sonification: Using ultrasound with plant matter in a solution, by cavitation shockwave. -Homogenizer: Shear force by forcing cells through tubes smaller than cells, by rotor- stator (rotating blade) or outer layer shear (French Press).

-Freezing: Cell rupture from freeze thaw process. Can take lots of time.

-High Temperature (and Pressure): Cells walls are disrupted, but denatures proteins, and heat can damage cell contents. Typically by autoclave, microwave, steam, etc.

Non-Mechanical Methods:

-Enzymes: Remove cell wall by using naturally occurring enzymes.

-Chemicals: Organic solvents like ethanol (alcohol), especially for hydrophobic (doesn’t like water) molecules. Commonly used with shearing forces.
-Bacteria: EDTA, negative bacteria, to chelate cations that bore holes in cell walls.

REF: http://bitesizebio.com/13536/bringing- down-the-walls-part-ii-8-methods-to-break- down-cell-walls/

 

Cell Lysis Methods:
Reagent Based Methods:
-Fast, efficient, reproducible
-Can extract total protein or subcellular fractions
-Disrupts cell wall and or lipid membrane

 

Physical Methods:
-Expensive equipment
-Larger footprint for equipment

-Less reproducible

-Not compatible with high-throughput and small volumes

-Aggregation and denaturation of protein may occur
-Cells disrupt at different times

REF: https://www.thermofisher. com/us/en/home/life-science/protein- biology/protein-biology-learning- center/protein-biology-resource-library/pierce- protein-methods/traditional-methods-cell-

 

 

Tensile Strength of Cell Walls

Cylindrical Cell Shape: 100 atm or 1,470 psi

Spherical Cell Shape: 95 atm or 1,396 psi

Spherical Cell Shape: 30 atm or 441 psi

REF: https://www.ncbi.nlm.nih. gov/pmc/articles/PMC1074911/pdf/plntphys0 0593-0165.pdf

Plant Cell Vacuoles

The central vacuole (may be 80 percent of space) is a membrane bound sac which provides cell support and helps the plant function with growth.

Turgor Pressure: Vacuoles help to maintain and control the rigidity of the cell (structure),

by compensating the osmotic pressure from within the cell and pressure exerted from outside the cell.

REF: https://micro.magnet.fsu.edu/cells/plants/vacuole.html

Additional Reading:

Cannabis sativa: The Plant of the Thousand and One Molecules

REF: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4740396/

 

Cell Disruption Using a Microfluidizer

Using a Microfluidizer versus a French Press using the same 20,000 psi back pressure, resulted in 92 percent breakage in 8 passes, versus only 50 percent breakge for the French Press in 7 passes.

REF: https://www.microfluidicscorp.com/sites/default/files/application-note-cell- disruption-publication-summaries.pdf

Practical Use of Continuous Processing in Developing and Scaling Up Laboratory Processes

Continuous flow reactors allow for better control of exothermic processing than do batch reactions, and allow for a more efficient and safe scale-up of rapid reactions in a smaller footprint.

REF: http://pubs.acs. org/doi/abs/10.1021/op0100605? journalCode=oprdfk

Supercritical Carbon Dioxide Extraction of Cannabinoids from Cannabis Sativa

PDF Link to Review: 20170714-infinity-supercritical-sco2-science-review

SEATTLE, WA  July 2017 (Infinity Supercritical Staff Article Review)

Supercritical fluid extraction with CO2 is already used on a large scale for botanical extraction due to its low cost, generally safe nature, and well known properties.

Reference science pdf article: Rovetto, Laura J., and Niccolo V. Aieta. Supercritical carbon dioxide extraction of cannabinoids from Cannabis sativa L.  The Journal of Supercritical Fluids (2017)

Supercritical (SC) CO2 properties, like density, and thus solvent power, change with temperature and pressure allowing for selectivity via tuning.

One can also use more polar co-solvents, like ethanol, to expand the extraction range of the low-polarity CO2 to include more polar components.

Previous research has shown two different optimal extraction parameters with SFE for terpenes and cannabinoids.

This study did not find a significant difference in extraction rate from 313-333 Kelvin (104- 140 F).
During the extraction time (during the linear trend before exhaustion), a yield of 0.00243g of extract/g of CO2, 0.00455g of extract/g of CO2, and 0.00666g of extract/g of CO2 was found for 17 MPa, 24 MPa, and 34 MPa respectively at 328K. 16.63 percent THC plant potency.

At 34 MPa, 0.0066g of extract/g of CO2, 0.01361g of extract/g of CO2, 0.00431g of extract/g of feed, and 0.00186g of extract/g of feed for the potencies 16.63 percent, 14.03 percent, 10.11 percent and 6.05 percent THC cannabis respectively.

Comparing using SC CO2 at 328K between 17, 24, and 34 MPa, the higher the pressure, the higher the yield, but lower the THC potency of the final mixture. 7.4 percent, 17.2 percent, 18.5 percent extract yield in comparison to total start weight; 76.23 percent, 70.63 percent, 69.41 percent THC potency for over 2 hours. 16.63 percent THC potency starting material and S/F ratios of 50 for high pressures, 100 for low.

At these temperature and pressures, partial decarboxylation takes place on the THCA to THC.

Higher Pressure = Lower Potency

They used a multi-stage depressurization chillers to precipitate the extract. Most of theTHC (and highest extract amount) was found in the first stage at 13 MPa (1,885 psi) and 328K (130 F), but was waxy, pasty, and darker in color. In the second and third separator MPa (1,305 psi) and 328K (130 F) and MPa (870 psi) and 298K (77 F), more fluid yellow color extract appeared.

Compared different potency cannabis (A 16.63 percent, B 14.03 percent, C 10.11 percent, and D 6.05 percent), leading to potencies of extract of A 69.41 percent, B 61.21 percent, C 57.86 percent, and D 56.06 percent total THC. Thus the more originally potent, the more potent the extract.

Extraction efficiency (in relation to THC) rises slightly as potencies decreases (A 89.89 percent, B 89.17 percent, C 90.31 percent, D 92.23 percent).

Extraction efficiency increases as potency decreases.

They attempted to use ethanol as a co- solvents. This would cause more additional process steps, unless you want to use winterization, in which case it does not heavily modify your process line.

No major difference between using 5 percent and 10 percent ethanol by weight in extraction, but noticeable decrease dropping to 2.5 percent. Thus 5 percent is an efficient amount of co-solvents. (328K 131 F, 34 MPa 4,931 psi, S/F 20)

If ethanol is used, use 5 percent.

With the conditions in 12, the plant material was exhausted within 50 minutes of extraction.

Ethanol pulses versus constant flow was compared and pulses either performed better, or the same as constant flow. (2 hour extraction, 5 percent by weight ethanol divided into 3 pulses at 0 minutes, 50 minutes and 110 minutes.)

Since plant material was at exhaustion by the 50 minute mark, only the first pulse was needed to be applied, meaning minimal ethanol is necessary.

Ethanol drastically decreases the SF ratio necessary for lower potencies cannabis to be extracted (only 60 percent of the mass of extract gained using ethanol achieved at 2 hours, compared to the 100 percent gained in 50 minutes).

Something not mentioned in the article, the residual THC in the exhausted plant material is about the same for the lower potency cannabis, implying that the 2 hour extraction extracts all the THC and the extra mass accumulated with the ethanol comes from additional cannabinoids.

Summary:

  1. Higher Pressure = Lower Potency

2. Extraction efficiency increases as potency decreases.

3. Ethanol cosolvent increases extraction, optimized at 5 percent ethanol added.

4. Pulsing performs better than constant flow.

 

 

 

 

 

Infinity Supercritical Introduces New Ultra-Efficient Organic Method of Botanical Oil Extraction

Press Release PDF

SEATTLE, June 20, 2017 (GLOBE NEWSWIRE) — Infinity Supercritical LLC, a leading manufacturer of botanical extraction equipment, announces the industry’s first organic method of oil extraction using distilled water as the solvent.

The new method involves a spinning disc reactor system which is being introduced into the industry for the extraction of oil from cannabis and hemp. The oil extract, called a concentrate, can be used in vape pens, edibles, and further processed into CBDs for medical and health purposes.

The system is so efficient that the process takes a few seconds, instead of hours or days, which is common in the industry now. In addition, the system uses distilled water as the solvent, instead of commonly used CO2, ethanol, or butane.

With a continuous feed system, different botanicals or varieties can be processed on-the-fly. Legacy batch systems can only process one botanical or variety at a time.

The equipment is modular and can be scaled up to any size. As a continuous feed, continuous flow process, batch systems are now obsolete. The smaller footprint results in lower initial acquisition, maintenance, and operational costs. The added benefit of a smaller continuous feed system is more efficient use of energy.

This process technology can also be used in other industrial applications, such as the production of biodiesel, nutraceuticals, and algae oil extraction. In the high-tech sector, the process can produce quantum dots, which have been identified as a future solar cell technology.

Infinity Supercritical LLC develops and markets innovative botanical oil extraction systems. Emphasis is placed on developing new technology to reduce extraction time, and producing a superior oil product, maximizing extracted antioxidants, terpenes, and nutrients. Industries served include cannabis, hemp, and hops. Please visit http://www.infinitysupercritical.com for more information.

 

 

400L Industrial Botanicals Extractor by Infinity

Infinity Supercritical is developing a 400L (100+ lbs/hr) industrial botanicals extraction system. This system uses common distilled water as the solvent, which provides a completely hydrocarbon or CO2 solvent free extraction method, which is the first organic extraction method to be introduced into the Cannabis industry.

The system is closed-loop and recycles the distilled water through a series of elegant, but simple, mechanical separation methods. The spent botanicals can be recycled and composed, or remediated through a add-on module which converts the plant matter to CO2 by using a patented system.

The system has other add-on high-tech innovation modules which can recover waste heat into electricity (Tribogen), a solid state chiller, ESP (electrostatic precipitation), and a Tesla disc pump. The system was developed, and uses the modular fluid handling device (US Patent 7726331), which is commonly referred to as the Modular Block, which was termed an industrial Lego by the National Science Foundation.

The modular system has a ROI payback within days, when used for processing legal Cannabis trim in a licensed facility.

The system can also be used for the continuous production of QD (Quantum Dots) which may be our future solar cell and battery technology. These are the same technologies that are being looked at and developed by Apple, Google, and Tesla.

 

Infinity Supercritical Introduces Industry First: Organic Botanical Oil Extraction

20170611-infinity-supercritical-organic-oil-extraction

Infinity is pleased to announce and industry first – organic oil extraction which does not use Butane or CO2. Using a food industry proven method called SDR (Spinning Disc Reactor), botanical oil can now be extracted at room pressure and temperature.

The benefits of a SDR system developed by Infinity Supercritical LLC (patented) are:

• Standard Room Temperature and Pressure Extraction

• Fast Reaction Time (measured in seconds)

• Continuous Feed Operation

• Uses Standard Distilled Water

• Organic Extraction (no additives to remove later)

• Industrial Volume Extraction (5-100+ lbs of input material per hour)

• Modular Compact System (can be built into a trailer or standard shipping container)

• Push Button Operation (no complex PLC or operator technique required – it just works)

The SDR can also be used in other industries, including the production of semi-conductor nanocrystals called Quantum Dots (QD).

This new systems provides a quantum leap forward in options available to botanical extraction production, by simplifying extraction technique (push a button) and monitor the continuous feed and flow. If Apple were to design a botanicals extraction system, this would be it.

 

 

 

California Cannabis Production | Start-up Cultivation vs Cash Flow | Strategy

Read the PDF: 20170608-infinity-supercritical-california-cannabis

California Cannabis

We are starting to get lots of calls from California regarding cultivation and using our extraction systems for oil production and sales for January 2018. The current strategy is to put up cultivation, and then start extraction after harvest. While this may seem intuitively correct, it is the worst strategy for cash-flow.

20170217-infinity-supercritical-10-liter-front-top

 

Start-up Cultivation Means Delayed Cash-flow

If you start with cultivation, you’re looking at 9 -12 months to begin getting cash-flow (in the process from building the grow-house to mature harvest). The time might be a bit better for pure indoor grow, but still a long time regardless. This means you will need a large amount of initial capital outlay, to build facilities, and during the grow. This is valuable time that can be better utilized.

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Start with Extraction of Oil for Cash-flow

 

The profit-makers out in the Cannabis industry have realized that while you can make money cultivating (which everybody is doing), faster access to cash-flow is from the value-added sector, of running extraction machines to produce live resin, shatter, crumb, concentrates for edibles, and vape- pen oil.

infinity-supercritical-co2-hops-extraction-flow-bar-1

Extraction Revenue

Don’t have your own Cannabis product ? Then check with your state regulations and purchase trim or other products from producers who do not have extraction facilities, and then work the value-added space. $50 a pound trim has the potential to get you more than $200 of oil extract. That’s a minimum of four times the value of the trim, and great cash-flow. Of course you will still need to look into the extraction license and other regulations, but this gets you started faster, and with less capital outlay.
 

Equity Versus Cash-flow

This type strategy gets you faster cash-flow and the all-important sales. This builds equity faster, and requires less initial capital. Starting with just a licensed extraction facility can provide you with a springboard of capital which you can leverage into your own indoor grow, or expanding extraction machinery and capabilities.

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Small Production and Post Processing With ExtractCraft | The Source Machine

PDF Review: 20170528-infinity-supercritical-extractcraft-review

Extraction Supplies 

Supercritical-CO2-Extraction | http://www.infinitysupercritical.com | http://www.extractcraft.com

The Source, which is manufactured by ExtractCraft, is a simple ethanol botanical oil extractor, that utilizes food grade alcohol as the solvent. This is a cool little piece of equipment, and with a little work, you can make outstanding extracts at home. There are many ways you could approach this and many more steps you could take than I am going to show here. For the purpose of this review, I will show a simple method that I have developed with some basic items:

-Ziplock bags

-Silicone rubber spatula

-Strainer

-Scissors

-Parchment paper

-Bottle of 95 percent pure food grade alcohol

-Cooler with dry ice

20170528-infinity-supercritical-review-01

 

Extract Botanical: Trim This is 25 grams of basic trim. This is nothing fantastic, but still contains some desirable oils.

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Moisture Removal: The simplist way to remove water is with dry ice in a cooler. This will help pull any remaining moisture through sublimation, and will also freeze most of the wax inside the material. Technique: Position the bag adjacent or on the dry ice. Keep the Ziplock bag open and close the cooler.

 

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Prepare The Source Machine:

Remove the lid from The Source and unscrew the reservoir cup.

 

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Add Food Grade (ethanol) Alcohol:

I like to fill the cup half way. This gets me about 8 oz of alcohol. If I was doing an extraction with some higher grade material, I would use one ounce of alcohol for every gram of botanicals. Since it’s trim, I am using one once of alcohol, for 4.25 grams of botanical.

Note: Never use methanol or anything but ethanol (just be safe and use the stuff you can buy at the liquor store). Anything but consumer edible ethanol may result in injury (blindness) if consumed.

20170528-infinity-supercritical-review-05

Add Alcohol to Ziplock Bag:

Pour the alcohol into a Ziplock bag and put it in the cooler with the dry ice.

 

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Cool With Dry Ice:

Dry ice is around (minus) -109 F. Getting everything this cold will help reduce the amount of wax removed during our extraction. I like to let it sit in the sealed up cooler for about 45 minutes, to an hour. You can go for longer if you wish, it all depends on the amount of moisture in your starting material.

 

20170528-infinity-supercritical-review-07

 

Add Chilled Alcohol With Botanicals:

Pour the chilled alcohol into the bag with the trim.

 

20170528-infinity-supercritical-review-08

 

Cool Botanicals with Alcohol in Cooler With Dry Ice:

After mixing the alcohol with our botanicals, set it back in on the dry ice and let it soak for 10-20 minutes. The alcohol is the solvent, and this is when the actual extraction occurs. If it soaks for 10 minutes or less you will usually get a nice golden extract. The longer its soaks the more chlorophyll you will absorb making your end extract much darker in color.

Longer Time = Solvent Releases wax and other products

 

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Prepare Removal of Alcohol And Extract:

Cut Corner of Ziplock bag.

 

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Pour Alcohol and Extracted Liquid:

Pour the liquid through the strainer. If you want filter the solution a couple times, you can use a coffee filter to get an extra clean solution.

 

20170528-infinity-supercritical-review-11

 

Set The Source Machine:

Screw the reservoir back in place, put the glass lid with the upper seal on and close the vacuum release screw. At this point if it’s plugged in you can just hit the green button and the process will start.

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Run the App:

Download the app, which allows you to control and monitor the process. When you start the process, the vacuum will turn on and the reservoir will begin to heat up. Remember the extraction process is all ready over. We are now boiling off and collecting the alcohol, so we can reuse it in future extractions.

 

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Small Pan Cooled Condenser:

There is a small pan included with The Source. It’s intended to be filled with ice to speed up the condensation of alcohol inside the top of the vacuum chamber. Fill with water and freeze overnight to use.

20170528-infinity-supercritical-review-14

 

Evaporating the Alcohol Using Heat:

Once the machine gets up to temperature, you can see small drops of alcohol forming on the sides and the top. It rolls off an gets caught in the collector at the bottom of the vacuum chamber. This is the alcohol evaporating and condensing.

 

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Mid-Process:

While the machine is processing, it is heating the alcohol, and it is evaporating. As the process goes continues, you can see the bubbles get smaller, as the level of solution goes down.

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Mid-Process Tincture Option:

If your end product is tincture, stop with the reservoir cup about 1/4 full. This will result in a potent tincture.

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Nearing End of Process:

When the alcohol is almost entirely boiled off you will see slow bubbles forming both large and small. This is something to watch and decide when you’re going to stop the process. I usually wait until the bubbles are very small and forming very slowly.

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End of Process:

As you learn technique, you will know when the process is near completion. Trial-and-error is your best guide. Write down the weight of liquid initially, then at the end, and log times.

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Final Product:

Use the silicone spatula to scrape out your extract and transfer on parchment paper. Let it sit overnight to evaporate any remaining alcohol. 12 hours gives it consistency for dabs or topping bowls. If you have a vacuum oven you can get a shatter consistency quit easily.

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Machine and Process Issues:

The downside to the machine/process is that some the alcohol finds it way into the bottom of the vacuum chamber, and is missed by the collector. It’s not a lot of alcohol, and is easy to wipe up. I use a paper towel to soak up the missed alcohol and use that to clean the reservoir cup.

Final Conclusion:

Overall I will say this is an easy and fun piece of equipment.

I would recommend it for any hobbyist extractor, and is an excellent addition to any kitchen.

Purchase Extraction Supplies At Our Amazon Store

 

 

 

 

 

 

Cannabis Oil Production For Profit

PDF Download: 20170302-infinity-supercritical-cannabis-oil-for-profit

Visit our Amazon Extraction Store for extraction and pen supplies.

Cannabis sweeps the nation

As the Cannabis revolution swings across America, states going legal are raking in huge tax revenue, and citizens are finally getting access to medical and recreational benefits of Cannabis production. The momentum is slowing moving towards oil (concentrates) which provide easier access to deliver the benefits via vape pens, edibles, and concentrates for medical purposes (CBD’s). With the political aspects aside, this review will list the aspects of producing Cannabis oil for profit.

20170217-infinity-supercritical-10-liter-front
Using a Infinity Supercritical 10L CO2 Extraction System is a good starting point for a oil refining business.

 

Supply versus demand

The mystique of the Cannabis industry has lots of people jumping into the mix, without knowledge of running a business, or the nuances of running a business to make money. A few are becoming millionaires, but most are breaking even, or losing money. Just look at the number of licenses issued in Colorado, and how supply has effected pricing. Business Insider reports that the price of wholesale marijuana has dropped by half in about a year.

http://www.businessinsider.com/marijuanas-getting-cheaper-in-colorado-2016-9

Plan a startup strategy

What differentiates those making money, and those losing money ?

Those who make money set out with a plan, a budget, funding, and a team to deliver that plan. If you set out with detailed goals and a strategy, you’re already ahead of most of the groups in the industry. Failure to plan, is a plan for failure.

You need to have a startup plan, growth, and exit plan. If you plan and play your cards right, you’ll end up with a successful business.

Information is paramount to profit

In the planning stages, it’s critical to become informed. Read, research, inquire, and educate yourself about what you are getting into.

Read: Study online information.

Research: Online studies, scientific research papers, pricing models and consumer demand.

Inquire: Existing successful operations, and those that are not, and why they are not.

Educate: Sometimes the key to success is a very fine line, stack the deck in your favor.

http://www.infinitysupercritical.com/publications.html

 

Determine your business path to success

Select the part of the industry, that interests you the most, and makes the most money.

While this may be easier said than done, select a industry segment that you will enjoy working in, and develop it.

If you are vertically integrated, and have lots of funding, you can run an entire operation from cultivation to retail sales. The savvy types will focus on one targeted segment and make money with that segment, then grow by acquisition.

 

Start with oil extraction

Who makes the most money in the oil industry ? When compared to the hydrocarbon oil industry, it is the refiners.

http://www.latimes.com/business/la-fi-gas-profits-20150722-story.html

In the Cannabis industry, the most value-added is extracting and refining the botanical oil.

http://blog.sfgate.com/smellthetruth/2015/01/12/is-cannabis-extraction-the-future-of-a-multi-billion-dollar-industry/

 

Why is Cannabis oil extraction potentially the most profitable and least vulnerable to industry pitfalls ?

While supply and demand will ultimately determine overall industry income, as a Cannabis oil refinery lab (including post processing), you have the flexibility to determine downstream products. With a extraction system, you can make live resin, vape pens, concentrates, shatter, etc. And like other industries, you can tailor the output according to the market demand. Cultivators and retails do not have such flexibility. The ability to morph according to customer demand is an important factor to profitability.

What is the best method of cultivation of Cannabis to make a methodical profit ?

The best profit model would be a indoor grow, with staggered starting and harvest cycles, on a weekly basis. This will not only utilize your energy, personnel, and extraction lab more efficiently, but also allows you to tailor downstream product offerings to consumer demand, while providing a fresh product at all times. While outdoor grows are great, they are only once a year. The stress at harvest season is tremendous, and all that supply drives prices down, at that time of year.

FogPonics is the best kept secret in the Cannabis industry

Developed by a LA entrepreneur, the vertical grow tower system provides a weekly harvest, optimizing energy, personnel, and production specifically targeting oil production. On a five week grow out cycle, FogPonics is designed for oil production with fast growth varieties like Cinderella.

 

Oil extraction and post production

As oil is extracted from botanicals, the end product is a substance commonly referred to as crude oil. While this material can be used for dabs, it is more likely to go into post processing for refining downstream into concentrates or other products. It is typical for a extraction system to have a complimentary post processing lab, to refine and separate the oil for consumer products.

 

Strategy for success

Determining your actual business model will depend on your goals and the market in your area, but we recommend the following:

1. Start a extraction facility with post-processing lab.

2. If supply is an issue, vertically integrate with a FogPonics vertical grow facility.

3. Tailor your output products to demand.

4. Start or acquire your own vape pen brand, or develop products with your concentrates.

ROI App: http://www.infinitysupercritical.com/roi.html

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